Anna Capasso, MD

Assistant Professor

20092018
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Colorectal Neoplasms Medicine & Life Sciences
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Aurora Kinases Medicine & Life Sciences
irinotecan Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences

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Research Output 2009 2018

Antitumor activity of the polo-like kinase inhibitor, TAK-960, against preclinical models of colorectal cancer

Klauck, P. J., Bagby, S. M., Capasso, A., Bradshaw-Pierce, E. L., Selby, H. M., Spreafico, A., Tentler, J. J., Tan, A. C., Kim, J., Arcaroli, J. J., Purkey, A., Messersmith, W. A., Kuida, K., Eckhardt, S. G. & Pitts, T. M., Feb 5 2018, In : BMC Cancer. 18, 1, 136.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Phosphotransferases
Cell Line
irinotecan
Inhibitory Concentration 50

A phase II clinical trial of the Aurora and angiogenic kinase inhibitor ENMD-2076 for previously treated, advanced, or metastatic triple-negative breast cancer

Diamond, J. R., Eckhardt, S. G., Pitts, T. M., van Bokhoven, A., Aisner, D., Gustafson, D. L., Capasso, A., Sams, S., Kabos, P., Zolman, K., Colvin, T., Elias, A. D., Storniolo, A. M., Schneider, B. P., Gao, D., Tentler, J. J., Borges, V. F. & Miller, K. D., Aug 2 2018, In : Breast Cancer Research. 20, 1, 82.

Research output: Contribution to journalArticle

Aurora Kinases
Triple Negative Breast Neoplasms
Phase II Clinical Trials
Angiogenesis Inhibitors
Microvessels

BRAF fusions identified in melanomas have variable treatment responses and phenotypes

Turner, J. A., Bemis, J. G. T., Bagby, S. M., Capasso, A., Yacob, B. W., Chimed, T. S., Van Gulick, R., Lee, H., Tobin, R., Tentler, J. J., Pitts, T., McCarter, M., Robinson, W. A. & Couts, K. L., Jan 1 2018, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Melanoma
Phenotype
Heterografts
RNA Sequence Analysis
Neoplasms
1 Citations

Cabozantinib exhibits potent antitumor activity in colorectal cancer patient-derived tumor xenograft models via autophagy and signaling mechanisms

Scott, A. J., Arcaroli, J. J., Bagby, S. M., Yahn, R., Huber, K. M., Serkova, N. J., Nguyen, A., Kim, J., Thorburn, A., Vogel, J., Quackenbush, K. S., Capasso, A., Schreiber, A., Blatchford, P., Klauck, P. J., Pitts, T. M., Eckhardt, S. G. & Messersmith, W. A., Oct 1 2018, In : Molecular Cancer Therapeutics. 17, 10, p. 2112-2122 11 p.

Research output: Contribution to journalArticle

Autophagy
Heterografts
Colorectal Neoplasms
Neoplasms
Growth

Dual compartmental targeting of cell cycle and angiogenic kinases in colorectal cancer models

Capasso, A., Pitts, T. M., Klauck, P. J., Bagby, S. M., Westbrook, L., Kaplan, J., Soleimani, M., Spreafico, A., Tentler, J. J., Diamond, J. R., Arcaroli, J. J., Messersmith, W. A., Eckhardt, S. G. & Leong, S., Oct 1 2018, In : Anti-Cancer Drugs. 29, 9, p. 827-838 12 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Cell Cycle
Phosphotransferases
Heterografts
Cell Line