George Georgiou, PhD

Professor; Professor (Medical)

1985 …2018
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Escherichia coli Medicine & Life Sciences
Antibodies Medicine & Life Sciences
Proteins Medicine & Life Sciences
Libraries Medicine & Life Sciences
Periplasm Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Single-Chain Antibodies Medicine & Life Sciences
beta-Lactamases Medicine & Life Sciences

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Research Output 1985 2018

Antibodies encoded by FCRL4-bearing memory B cells preferentially recognize commensal microbial antigens

Liu, Y., McDaniel, J. R., Khan, S., Campisi, P., Propst, E. J., Holler, T., Grunebaum, E., Georgiou, G., Ippolito, G. C. & Ehrhardt, G. R. A., Jun 15 2018, In : Journal of Immunology. 200, 12, p. 3962-3969 8 p.

Research output: Contribution to journalArticle

Palatine Tonsil
Microbiota
Gene Frequency
B-Lymphocytes
Phenotype
7 Citations

Functional interrogation and mining of natively paired human v H:V L antibody repertoires

Wang, B., Dekosky, B. J., Timm, M. R., Lee, J., Normandin, E., Misasi, J., Kong, R., McDaniel, J. R., Delidakis, G., Leigh, K. E., Niezold, T., Choi, C. W., Viox, E. G., Fahad, A., Cagigi, A., Ploquin, A., Leung, K., Yang, E. S., Kong, W. P., Voss, W. N. & 13 othersSchmidt, A. G., Moody, M. A., Ambrozak, D. R., Henry, A. R., Laboune, F., Ledgerwood, J. E., Graham, B. S., Connors, M., Douek, D. C., Sullivan, N. J., Ellington, A. D., Mascola, J. R. & Georgiou, G., Feb 1 2018, In : Nature Biotechnology. 36, 2, p. 152-155 4 p.

Research output: Contribution to journalArticle

Neutralizing Antibodies
Antibodies
Influenza Virus Hemagglutinin Glycoproteins
HIV-1
Ebolavirus

High-affinity IgA against microbial glycans

Lee, J. & Georgiou, G., Jun 1 2018, In : Nature Immunology. 19, 6, p. 514-515 2 p.

Research output: Contribution to journalShort survey

O Antigens
Antibody Affinity
Klebsiella pneumoniae
Immunoglobulin A
Polysaccharides
3 Citations

Identification of tumor-reactive B cells and systemic IgG in breast cancer based on clonal frequency in the sentinel lymph node

McDaniel, J. R., Pero, S. C., Voss, W. N., Shukla, G. S., Sun, Y., Schaetzle, S., Lee, C. H., Horton, A. P., Harlow, S., Gollihar, J., Ellefson, J. W., Krag, C. C., Tanno, Y., Sidiropoulos, N., Georgiou, G., Ippolito, G. C. & Krag, D. N., May 1 2018, In : Cancer Immunology, Immunotherapy. 67, 5, p. 729-738 10 p.

Research output: Contribution to journalArticle

B-Lymphocytes
Immunoglobulin G
Breast Neoplasms
Neoplasms
Immunotherapy
17 Citations

Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies

Chen, Y. Q., Wohlbold, T. J., Zheng, N. Y., Huang, M., Huang, Y., Neu, K. E., Lee, J., Wan, H., Rojas, K. T., Kirkpatrick, E., Henry, C., Palm, A. K. E., Stamper, C. T., Lan, L. Y. L., Topham, D. J., Treanor, J., Wrammert, J., Ahmed, R., Eichelberger, M. C., Georgiou, G. & 2 othersKrammer, F. & Wilson, P. C., Apr 5 2018, In : Cell. 173, 2, p. 417-429.e10

Research output: Contribution to journalArticle

Neuraminidase
Human Influenza
Antibodies
Viruses
Infection